Ground Water Quality Effects on Domestic Water Utilization

The work upon which this report is based was supported in part by funds (Project A-040-ALAS) provided by the United States Department of the Interior, Office of Water Resources Research, as authorized under the Water Resources Act of 1964, as amended

Integrating Geriatrics in Primary Care: Progress and Prospects

Educational Objectives 1. Demonstrate the need for primary care redesign to better meet the needs of older patients. 2. Identify prospective redesign solutions. 3. Appreciate educational implication that redesign engenders

Richtags: Cross Repository Browsing

richtags allows you to search across multiple repositories from numerous institutions covering hundreds of disciplines for research that is of interest to you

mSpace meets EPrints: a Case Study in Creating Dynamic Digital Collections

In this case study we look at issues involved in (a) generating dynamic digital libraries that are on a particular topic but span heterogeneous collections at distinct sites, (b) supplementing the artefacts in that collection with additional information available either from databases at the artefact's home or from the Web at large, and (c) providing an interaction paradigm that will support effective exploration of this new resource. We describe how we used two available frameworks, mSpace and EPrints to support this kind of collection building. The result of the study is a set of recommendations to improve the connectivity of remote resources both to one another and to related Web resources, and that will also reduce problems like co-referencing in order to enable the creation of new collections on demand

Calibration of neural networks using genetic algorithms, with application to optimal path planning

Genetic algorithms (GA) are used to search the synaptic weight space of artificial neural systems (ANS) for weight vectors that optimize some network performance function. GAs do not suffer from some of the architectural constraints involved with other techniques and it is straightforward to incorporate terms into the performance function concerning the metastructure of the ANS. Hence GAs offer a remarkably general approach to calibrating ANS. GAs are applied to the problem of calibrating an ANS that finds optimal paths over a given surface. This problem involves training an ANS on a relatively small set of paths and then examining whether the calibrated ANS is able to find good paths between arbitrary start and end points on the surface

mSpace Mobile: Exploring Support for Mobile Tasks

In the following paper we compare two Web application interfaces, mSpace Mobile and Google Local in supporting location discovery tasks on mobile devices while stationary and while on the move. While mSpace Mobile performed well in both stationary and mobile conditions, performance in Google Local dropped significantly. We postulate that mSpace Mobile performed so well because it breaks the paradigm of the page for delivering Web content, thereby enabling new and more powerful interfaces to be used to support mobility

Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome

Background: Sepsis is one of the leading causes of death in the UK. Aims: The aims of this study were to identify the rate of inactive antimicrobial therapy (AMT) in the ICU and whether inactive AMT had an effect on in hospital mortality, ICU mortality, 90-day mortality and length of hospital stay. Additionally, we wanted to identify risk factors for receiving inactive AMT. Methods: This was a retrospective observational study conducted at Glasgow Royal Infirmary ICU between January 2010 and December 2013, with 12,000 blood cultures taken over this time period, of which n=127 were deemed clinically significant. Multivariate logistic regression was used to identify risk factors independently associated with mortality. To identify risk factors for receiving inactive AMT a univariable and a subsequent multivariate analysis was constructed. Results: The rate of inactive AMT was 47% (n =60). Our multivariate analysis showed that receiving antibiotics within the first 24 hours of ICU admission led to a reduced mortality (RR 1.70; 95% CI 1.19-2.44.) Furthermore, it showed that severity of illness (as defined by SIRS criteria sepsis vs septic shock) increased mortality (OR 9.87; 95% CI 1.73-55.5). However, inactive AMT did not increase mortality (OR 1.07; 95% CI 0.47-2.41) or length of hospital stay (53.2 vs 69.1 days p=0.348.) We identified fungal bloodstream infection as a risk factor for receiving inactive AMT (OR 5.10;95% CI 1.29-20.14. Conclusion: Mortality from sepsis is influenced by multiple factors. We were unable to demonstrates that inactive AMT had an effect on mortality in sepsis